Adverse drug reactions have led to a significant number of emergency room visits in America. These unwanted side effects are sometimes caused by drug to gene interactions of individual patients. The American Medical Association recommends that physicians across the country gain a deeper understanding of the link between a patient’s genetic predisposition and how medications may affect them.

Medication arranged in the shape of a DNA double helix

What Is Pharmacogenetics?

Pharmacogenetics is the study of how genetic differences among individuals cause varied responses to a drug.  Occasionally these responses are in the form of unwanted side effects.  Doctors do their best to prescribe medications in dosages appropriate to their patient.  Using information such as known allergies, blood type, age, and gender to make these treatment decisions.  However, if a Doctor were able to peek into the genetic makeup of their patient as well it would paint a much more accurate picture.  The genetics of a person will reveal how that individual will react to a medication whether it be a positive or negative outcome.  Taking this measure would help to prevent the unwanted side effects.  Physicians can order pharmacogenetic testing from TruGenX through our website.

Understanding Drug Metabolization

When we take medicine, our bodies must break it down or metabolize it. Our bodies use enzymes to break down the active ingredients in most medicines. How individuals metabolize medications varies based on their genetics. Some people are poor metabolizers and some people are rapid metabolizers. If you are an outlier, your physician may need to change your dosage or prescription to optimize your treatment.

Benefits of Pharmacogenetic Testing

  • Precision Medicine: Pharmacogenetics helps patients and medical providers find the right medication & dosage, eliminating the “trial and error” method.
  • Saving Money: Pharmacogenetics also helps patients to avoid wasting money on medicine that does not work.
  • Safety: With pharmacogenetic testing, patients can avoid potentially risky or dangerous adverse side effects.
  • Time: Pharmacogenetic tests help patients to quickly find the right medication for their treatment without spending weeks or months using the trial and error method.

When to Ask Your Doctor About Pharmacogenetic Testing

At Risk Patients

Patients who are at a greater risk of complications that may occur after an adverse drug reaction should consider pharmacogenetic testing. This includes patients over the age of 65.

Issues with Medication

If you have a history of any medication not working or experiencing unwanted side effects due to a medication, you should speak to your doctor about pharmacogenetic testing.

Pre-Existing Conditions

If a patient has a pre-existing condition including acid reflux, peptic ulcers, or asthma. They may want to talk to their doctors about pharmacogenetic testing before going on a new medication.

Pregnancy

Pregnant women should talk to their doctor about pharmacogenetic testing if they are about to start a new medical treatment.

What drugs does Pharmacogenetic testing cover?

TruGenX offers pharmacogenetic testing that covers the major enzymes (Cytochrome P-450) involved in metabolizing specific medications. The FDA has updated the labels of more than 250 different prescription medications to contain information on pharmacogenetics and metabolization. 

Order Pharmacogenetic Testing from TruGenX

TruGenX offers molecular testing to doctors and physicians nationwide. We only provide our kits to licensed medical professionals. If you are a patient and believe you may benefit from pharmacogenetic testing, talk to your doctor about ordering tests. If you are a licensed medical professional and would like to order testing kits, please contact TruGenX or use our online ordering feature.