Do you experience recurrent Urinary Tract Infections?​

Learn how Real-time PCR can help optimize your UTI care.​

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Molecular Diagnostics / Polymerase Chain Reaction (PCR) UTI Test

Urinary Dipstick Test

Culture Based Testing

Indications – Molecular Diagnostics for UTI

  • Recurring UTIs
  • Interstitial Cystitis
  • Pyelonephritis
  • Pregnancy
  • Over 50 Years of Age
  • Chronic Pain Care Patients
  • Immunocompromised Patients
  • Very Young

Recurring UTI’s

Increasing multidrug resistance in uropathogens is leading to high recurrence rate of UTI’s with blanket usage of antibiotics

Interstitial Cystitis

Culture-based testing alone misses up to 67% of UTI infections and cannot identify polymicrobial infections. Sometimes unexplained symptoms are classified as Interstitial Cystitis whereas the patient may have a chronic, embedded infection3

Pyelonephritis

Antibiotics are first course of treatment. The type of antibiotic prescribed depends on whether or not the bacteria can be identified, otherwise broad-spectrum antibiotics are used

Pregnancy

40% of pregnant women with asymptomatic bacteriuria will develop Pyelonephritis, which can cause pre-term delivery and low birth rates6

Risk Factors

  • Previous antibiotic use
  • Ethnicity
  • Recent Travel
  • Nursing home Residence
  • Catheterization
  • Previous Hospitalization
  • Diabetes

Over 50 Years in Age

More prone to UTI’s as assortment of ailments can cause urinary retention. Does not take into account UTI misdiagnosis which may be as high as 67%. Studies have also shown 39% of elderly patients present with polymicrobial infections which cannot be diagnosed via Culture7 3

Chronic Pain Care Patients

Are especially susceptible to UTI’s as a side effect of pain medications: infections are more serious by the time they are detected

Pyelonephritis

Antibiotics are first course of treatment. The type of antibiotic prescribed depends on whether or not the bacteria can be identified, otherwise broad-spectrum antibiotics are used

Pregnancy

40% of pregnant women with asymptomatic bacteriuria will develop Pyelonephritis, which can cause pre-term delivery and low birth rates6

19U - UTI Panel, PCR and Resistance Markers

Gram Negative Organisms

Gram Positive Organisms

Fungi

Resistance Markers

  • KPC Carbapenem Resistance
  • CTX-M group 1 Extended Spectrum-Betalactamase
  • vanA1 Vancomycin resistance
  • vanB Vancomycin resistance
  • vanA2 Vancomycin resistance

Applicable ICD-10 Codes - Molecular UTI Test

N30.00Acute cystitis without hematuria
N14.0Analgesic nephropathy
R82.71Bacteriuria
N20.0Calculus of kidney
N20.2Calculus of kidney with calculus of ureter
N71.1Chronic inammatory disease of uterus
N11.90Chronic tubulo-interstitial nephritis, unspecied
N30.90Cystitis, unspecied without hematuria
N42.9Disorder of prostate, unspecied
R30.00Dysuria
N18.6End stage renal disease
N73.9Female pelvic inammatory disease, unspecied
R50.9Fever, unspecied
N14.1Nephropathy induced by other drugs, medicaments and biological substances
N14.2Nephropathy induced by unspecied drug, medicament and biological substance
N34.1Nonspecic urethritis
R82.99Other abnormal findings in urine
R82.79Other abnormal findings on microbiological examination of urine
N28.89Other specified disorders of kidney and ureter
N76.89Other specified inammation of vagina and vulva
A41.9Sepsis, unspecified organism
N14.4Toxic nephropathy, not elsewhere classied
R82.90Unspecied abnormal findings of urine
N05.2Unspecied nephritic syndrome with diuse membranous glomerulonephritis
N05.1Unspecied nephritic syndrome with focal and segmental glomerular lesions
N05.0Unspecied nephritic syndrome with minor glomerular abnormality
N05.9Unspecied nephritic syndrome with unspecied morphologic changes
N34.3Urethal syndrome, unspecied
N20.9Urinary calculus, unspecied
N39.0Urinary tract infection, site not specied
R.82.81Pyuria
R30.9Painful micturition, unspecied
N45.1Epididymitis

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Sample Report

an example of a test from TruGenX
Click to View Report

Request Test Kits

Please indicate the quantity of test kits you would like to receive, then proceed to the next page to confirm your shipping and contact information. Please note: complimentary sample kits are only available to licensed medical professionals.

1 “Urinary Tract Infections.” National Kidney Foundation, https://www.kidney.org/sites/default/les/uti.pdf
2 Jung C, Brubaker L, “The etiology and management of recurrent urinary tract infections in postmenopausal women,” Climacteric 2019 January 9: 1-8.
3 Price TK, Dune T, Hilt EE, Thomas-White KJ, Kliethermes S, Brincat C, Brubaker L, Wolfe AJ, Mueller ER, Schreckenberger PC. 2016. “The clinical urine culture: enhanced techniques improve detection of clinically relevant microorganisms.”
J Clin Microbiol 54:1216–1222. “doi:10.1128/JCM.00044-16.
4 S. Heytens. L. Coorevits. Boelens. Van Simaey. Christiaens.”Women with symptoms of a urinary tract infection but a negative urine culture: PCR-based quantication of Escherichia coli suggests infection in most cases” Clinical Microbiology
and Infection Volume 23, Issue 9, September 2017, Pages 647-652
5 J Clin Microbiol “The Clinical Urine Culture: Enhanced Techniques Improve Detection of Clinically Relevant Microorganisms” 2016 May; 54(5): 1216–1222. Published online 2016 Apr 25. Prepublished online 2016 Mar 9. doi: 10.1128/JCM.00044-16
6 Smaill FM, Vazquez JC. “Antibiotics for asymptomatic bacteriuria in pregnancy.” Cochrane Database Syst Rev 2007;2:CD000490
7 J. Alter. Andrea Cronican. “THE IMPACT OF POLYMICROBIAL INFECTIONS ON URINARY TRACT INFECTIONS & ANTIBIOTIC RESISTANCE” A DIAGNOSTICS SOLUTIONS COMPANY