Respiratory Tract Infection

  • Respiratory infections cause more doctor visits and absences from school and work than any other illness.1
  • Most people experience an average of 2 respiratory infections each year; these infections can lead to severe disease in high risk populations, which include young children, the elderly, and anyone with weakened or compromised immune systems.2
  • Only 16% of positive results are Influenza A3, underscoring need for more rapid, accurate and comprehensive testing platforms.
  • While culture-based testing historically is the Gold Standard, RT-PCR RPP tests for multiple pathogens from a single specimen and is more sensitive and specific.

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Please indicate the quantity of test kits you would like to receive, then proceed to the next page to confirm your shipping and contact information. Please note: complimentary sample kits are only available to licensed medical professionals.

Polymerase Chain Reaction (PCR) Respiratory Pathogen Panel RPP Test

  • Rapid - Improves speed and accuracy of respiratory pathogen detection in a matter of hours versus days with culture-based testing
  • Accurate - Identication of 9 bacterial pathogens and 26 Viral pathogens from a single specimen
  • Comprehensive - PCR allows for earlier intervention, improved patient outcomes via optimized therapy with our Respiratory Pathogen Panel
  • Our Respiratory Pathogen Panel (RPP) tests for common pathogens which may be bacterial or viral. Real Time-Polymerase Chain Reaction testing (RT-PCR) quickly aides in pathogen identication which can discourage unnecessary antibiotic usage and optimized patient care

Culture Based Testing

  • Turnaround time for conventional virus detection methods ranges from approximately 2 to 3 hours for Direct Fluorescent Antibody test (DFA) to 2 to 3 days for Culture Augmented-Direct Fluorescent Antibiody test (CA-DFA) and up to 1 to 2 weeks for virus isolation. The m-RT-PCR-ELAHA assay, on the other hand, had a turnaround time for results that was less than 5 hours4
  • Many clinically relevant viruses are difficult to grow in culture (such as rhinovirus and coronavirus) and may produce variable results
  • Rapid laboratory diagnosis of HRSV (Human Respiratory Syncytial Virus) infection in children and infants can be critical for effective patient management by focusing appropriate drug treatment, reducing unnecessary use of antibiotics, and preventing nosocomial spread

Our Respiratory Pathogen Panel

9 Bacterial Pathogens Detected

Target Organism Assay name
Bordetella bronchiseptical parapertussis / pertussis Bordetella
Bordetella pertussis B. pertussis
Chlamydophila pneumoniae C. pneumoniae
Haemophilus inuenzae H. inuenzae
Klebsiella pneumoniae K. pneumoniae
Legionella pneumophila L. pneumophila
Mycoplasma pneumoniae M. pneumoniae
Staphylococcus aureus S. aureus
Streptococcus pneumoniae S. pneumoniae

26 Viral Pathogens Detected

Target OrganismAssay name
Human BocavirusHBoV
Human Coronavirus 229ECoV_229E
Human Coronavirus HKU1CoV_HKU1
Human Coronavirus NL63CoV_NL63
Human Coronavirus OC43CoV_OC43
Human Enterovirus [pan assay]EV_pan
Human Enterovirus D68EV_D68
Human Metapneumovirus (hMPV)hMPV
Human Parainuenza virus 1hPIV1
Human Parainuenza virus 2hPIV2
Human Parainuenza virus 3hPIV3
Human Parainuenza virus 4hPIV4
Human Respiratory Syncytial Virus A (RSVA)RSVA
Human Respiratory Syncytial Virus B (RSVB)RSVB
Human Rhinovirus 1/2RV_1of2
Human Rhinovirus 2/2RV_2of2
Human herpesvirus 3 [HHV3 – Varicella zoster Virus]HHV3
Human herpesvirus 4 [HHV4 – Epstein-Barr Virus]HHV4
Human herpesvirus 5 [HHV5 – Cytomegalovirus]HHV5
Human herpesvirus 6 [HHV6]HHV6
Inuenza AFlu_A_pan
Inuenza A/H1-2009FLu_A_H1
Inuenza A/H3FLu_A_H3
Inuenza BFLu_B_pan

High Risk Groups

  • Children younger than 5 - especially children less than 2 years old
  • Adults 65 years of age and older
  • Pregnant women
  • Critically ill patients - especially immunocompromised, (i.e. cancer and transplant patients)

Clinical Benefits

  • Rapid detection of multiple pathogens from a single specimen, often in hours.
  • Accurate and Comprehensive Results
  • Better Patient Outcomes
  • Antibiotic Stewardship

Sample Report

A sample Respiratory Pathogen Panel Test
Click to View Report

Request Test Kits

Please indicate the quantity of test kits you would like to receive, then proceed to the next page to confirm your shipping and contact information. Please note: complimentary sample kits are only available to licensed medical professionals.

1) Johns Hopkins Medicine Health Library.,P02966 (accessed February 2016)
2) American College of Physicians: A Guide to Managing Respiratory Infections. Breathe Easy. 2008
3) Schreckenberger, P. and McAdam, A. (2015). Point-Counterpoint: Large Multiplex PCR Panels Should Be First-Line Tests for Detection of Respiratory and Intestinal Pathogens. J Clin Microbiol. 53(10):3110-5. doi: 10.1128/JCM.00382-15
4) Journal of Molecular Diagnostics, Vol. 6, No. 2, May 2004 Copyright © American Society for Investigative Pathology and the Association for Molecular Pathology A Sensitive, Specific, and Cost-Effective Multiplex Reverse Transcriptase-PCR Assay for the Detection of Seven Common Respiratory Viruses in Respiratory Samples Melanie W. Syrmis,*†‡ David M. Whiley,*† Marion Thomas,‡ Ian M. Mackay,*†‡ Jeanette Williamson,§ David J. Siebert,§ Michael D. Nissen,‡ and Theo P. Sloots*†‡§
5) Point: is the era of viral culture over in the clinical microbiology laboratory Hodinka RLJ Clin Microbiol. 2013 Jan; 51(1):2-4.
6) J Clin Microbiol. 2002 Dec; 40(12): 4418–4422. doi: 10.1128/JCM.40.12.4418-4422.2002PMCID: PMC154614PMID: 12454129
Detection of Human Respiratory Syncytial Virus in Respiratory Samples by LightCycler Reverse Transcriptase PCRDavid M. Whiley, 1,2 Melanie W. Syrmis,1,2,3 Ian M. Mackay,1,2,3 and Theo P. Sloots1,2,3,4,*