HTR2A Gene Testing
HTR2A is a post-synaptic receptor of serotonin. This receptor binds serotonin and amplifies excitatory signals of neurons in the brain. HTR2A is found throughout multiple regions of the brain. Serotonin is very important in the study of and administration of antidepressants and antipsychotic prescription medications. Gene variations that affect HTR2A are likely to affect medications designed to mitigate serotonin absorption.
Genetic Variations' Affects on Antidepressants
A large benefit of PGx (pharmacogenetic) tests is that they provide physicians and patients with valuable information that can be used to predict and prevent adverse reactions with specific medications. As mentioned above, HTR2A genetic variation affects how a patient interacts with psychiatric medications. With the help of of PGx testing, patients can avoid potential issues and also decrease the length of time needed to find the right medication and dosage that works for them. There are a variety of reasons to order PGx testing for a patient. If a patient is about to begin treatment with a known medication that has pharmacogenetic research (the FDA has required 250 different cardiac and psychiatric medications to display pharmacogenetic medication) it would be beneficial to order a test. Additionally, if a patient is actively taking a medication and they are experiencing side effects or medication inefficacy, PGx testing can help. Finally if the patient has a family history of specific medications proving to be ineffective, PGx can help rule out potential treatments by studying genetic variations that may affect your patient.
Order PGx Testing for Psychiatric Medications
PGx testing is invaluable for patients and physicians. Not only does it lead to quicker and better outcomes, but it also helps prevent life-threatening adverse reactions. If you are a patient or an individual interested in learning more about these tests please visit our resources on PGx testing. Physicians can order tests for their patients via our contact page.